Cardiac Stem Cell Therapy for Cardiac Repair
نویسندگان
چکیده
منابع مشابه
Cardiac Stem Cell Therapy for Cardiac Repair
OPINION STATEMENT The discovery of adult cardiac stem cells (CSCs) and their potential to restore functional cardiac tissue has fueled unprecedented interest in recent years. Indeed, stem-cell-based therapies have the potential to transform the treatment and prognosis of heart failure, for they have the potential to eliminate the underlying cause of the disease by reconstituting the damaged hea...
متن کاملStem cell therapy for cardiac repair.
Heart regeneration via stem cell therapy could improve the functional outcome for millions of patients. A goal of cardiac stem cell research is to foster the engraftment of new, beating cardiac cells into the ischemic region of the heart after a myocardial infarction. The key elements of cell therapy for myocardial repair reviewed here are the source of cells and the mechanisms by which these c...
متن کاملCell therapy for cardiac repair.
Heart failure is a leading cause of morbidity and mortality worldwide. The current strategies for treatment are limited and new therapeutic approaches are needed. This review describes research performed in animal models of cardiac disease and clinical trials and discusses the mechanisms involved in possible beneficial effects of cell therapy. Cell therapy is a promising strategy to treat heart...
متن کاملStem cell therapy for cardiac repair: benefits and barriers.
Cardiovascular disease remains the leading cause of death worldwide. Acute ischaemic injury and chronic cardiomyopathies lead to permanent loss of cardiac tissue and ultimately heart failure. Current therapies aim largely to attenuate the pathological remodelling that occurs after injury and to reduce risk factors for cardiovascular disease. Studies in animal models indicate that transplantatio...
متن کاملStem cell differentiation: cardiac repair.
Cellular transplantation has been employed for several years to deliver donor cardiomyocytes to normal and injured hearts. Recent reports of a variety of stem cells with apparent cardiomyogenic potential have raised the possibility of cell transplantation-based therapeutic interventions for heart disease. Here we review the preclinical studies demonstrating that intracardiac transplantation of ...
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ژورنال
عنوان ژورنال: Current Treatment Options in Cardiovascular Medicine
سال: 2014
ISSN: 1092-8464,1534-3189
DOI: 10.1007/s11936-014-0324-3